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Updated: April 2024

The second half of the 2022 Major League Baseball season has just started and now is the perfect time to place a bet or two on who you think will win the 2022 World Series.

After the All-Star break is a great time to see where teams stand in the playoff picture. Each team has already played over 90 games and the contenders for a division title and wild card spots have mostly separated themselves from the rest of the pack. Although a lot can happen over the final two months of the season, the teams with the best chance of making it to the World Series are taking shape.


Let’s take a look at the American League first.

The Boston Red Sox, Cleveland Indians and the Houston Astros are currently residing atop their respective divisions. However, the Astros have the best odds of winning the World Series among the division leaders at +410, according to 5Dimes sportsbook.


Unsurprisingly, the Astros have a pair of heavyweights, the Red Sox at +465 and New York Yankees at +535, chomping at their heels.

One team that could overthrow the American League favorites are the Indians, which odds to reach the Fall Classic currently sit at +1300. The Indians boosted their porous bullpen with the addition of San Diego Padres closer Brad Hand, and will welcome back ace reliever Andrew Miller later this month.


The Seattle Mariners and Los Angeles Angels figure to clash for the final wild card spot, but the Mariners are the favorites at +2500.

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In the National League, the Philadelphia Phillies, Chicago Cubs and Los Angeles Dodgers are the division front-runners with the Dodgers leading the pack at +850 to win the World Series. Los Angeles just added All-Star shortstop Manny Machado to an already potent batting lineup and have posted a 10-4 record in July.


The Cubs are currently at +950 and held a three game lead over the Milwaukee Brewers at the break. The Brewers are tied with the Atlanta Braves at +2150 as the fifth-best teams on the senior circuit.

The Phillies are sitting at +1625 and have a slim half-game lead over the Braves, while the Arizona Diamondbacks odds of reaching the World Series is at +2000 despite trailing the Dodgers by less than one game.


Several teams have seen little or no movement since their Opening Day projections. The Angels and the St. Louis Cardinals chances of winning the World Series remain the same, at +30000 and +5000, respectively.


The San Francisco Giants started the season at +5000 and are currently at +4000.


While the current future trends will disappoint fans in Philadelphia and Seattle, it's possible that a rematch of last year's World Series will materialize. But a trio of strong contenders in the American League and a handful of squads in the National League could make a postseason run of their own.


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As betting on sports becomes more popular all over the globe, it can attract some negative attention from the sports franchises and teams that are being bet upon.

With millions of dollars riding on each game, some unscrupulous sports teams or players attempt to fix the outcome. Most of us have seen the scandals highlighted in the newspaper or on TV. Despite these occasional trouble spots, sports betting remains a popular pastime for many fans.