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2022 NFL Week 2 Predictions
Updated: November 2022



Arizona Cardinals vs Las Vegas Raiders (-5)

How to watch: Sunday, 4:25 PM ET, CBS

Cardinals @ Raiders - A major problem Arizona has right now is the injury bug as Rondale Moore had an injured hamstring at wide receiver, cornerback Trayvon Mullin had an injured toe and offensive linemen Justin Pugh had a neck injury. As for the Raiders they are going to have to do a better job of keeping Derek Carr off the ground who got sacked five times in week 1. Pick: Raiders -5


Cincinnati Bengals (-7) vs Dallas Cowboys

How to watch: Sunday, 4:25 PM ET, CBS

Bengals @ Cowboys -Just like any game with two elite quarterbacks it will all come down to who makes the smarter plays which means that Bengals quarterback Joe Burrow absolutely can’t have the start that he did in week 1 against the Steelers when he threw four interceptions. Pick: Bengals -7


Chicago Bears vs Green Bay Packers (-8)

How to watch: Sunday, 8:20 PM ET, NBC

Bears @ Packers This game will be the Packers second attempt at proving that the front office did not screw up by getting rid of Davante Adams was a mistake as they only scored one touchdown in their season opener against Minnesota. As for the Bears they are going to have to either get much better on third down or increase their number of long plays as they only went 5-14 on third down in their season opener. Pick: Bears +8


Tennessee Titans vs Buffalo Bills (-10)

How to watch: Monday, 7:15 PM ET, ESPN

Titans @ Bills This Monday night showdown, which will probably not be the last Monday night showdown, is a rivalry that will last for many years into the future as these are two of the more promising and upcoming teams in the NFL. The key matchups in this one is Derrick Henry versus the Bills defensive front, which is one of the best in the NFL and as always is with all teams when it comes to the Bills, how well the Titans can contain (or not) Josh Allen. Pick: Bills -10


Minnesota Vikings vs Philadelphia Eagles (-2.5)

How to watch: Monday, 8:30 PM ET, ABC

Vikings @ Eagles - This game has the potential to be another offensive showing as both Kirk Cousins and Jalen Hurts showed dominant performances in their season opener. Usually when you have two teams who have elite offenses it comes down to which team will get the big stop first. Pick: Vikings +2.5 Sportsbook
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2020 Game Predictions


Cincinnati Bangels @Cleveland Browns
Thursday, September 17th, 2020
Betting Line: Browns -6, O/U 43.5

Two inept Ohio teams meet on a Thursday night to kick off Week 2. The Browns once again hyped up 2020 as the season in which the tide would turn. They laid an egg last week against Baltimore. The Bengals and rookie quarterback Joe Burrow almost pulled off an upset of the Chargers last week. Cleveland has the better roster and they’re at home… CLEVELAND 23, CINCINNATI 17


NY Giants @ Chicago Bears

Sunday, September 20th, 2020
Betting Line: Bears -5.5, O/U 42.5

The Bears came back to beat the Lions last week. They faced the Giants at home last year and won 19-14. In fact, Chicago has beaten the Giants at home each of the last two times the teams have met at Soldier Field. The Giants are young and playing on the road in Week 2 won’t help… CHICAGO 20, N. Y. GIANTS 17


Atlanta Falcons @ Dallas Cowboys
After a loss to the Rams on the road, Dallas returns home to face the Falcons. Atlanta is one of the teams that could be a surprise in 2020. They lost last week to Seattle, but have an offense led by Matt Ryan, Julio Jones, and Todd Gurley that can score. The last time the Falcons played in Dallas they won 39-28. Is an upset brewing? ATLANTA 27, DALLAS 25


Detroit Lions @ Green Bay Packers
The Lions have had some success recently against Green Bay. Don’t let that fool you. Detroit held a 23-6 lead over Chicago last week and let it slip away. Aaron Rodgers threw four touchdown passes last week as the Packers left no doubt as to who rules the NFC North… GREEN BAY 37, DETROIT 23


Jacksonville Jaguars @ Tennessee Titans
The Titans own this series with Jacksonville, especially when Tennessee is playing at home. The Titans have won five of the last six meetings and haven’t lost at home to the Jags since 2013. The Titans ground game is strong with Derrick Henry and the defense is stout. The Jags won an upset last week, but it won’t happen again… TENNESSEE 28, JACKSONVILLE 17


Ninnesota Vikings @ Indianapolis Colts
Neither the Colts nor the Vikings want to start the season 0-2, but one of them will after Sunday. The teams don’t meet often, but Indianapolis has won all five games played since 2000. The Colts lost leading rusher Marlon Mack for the season. The Vikings defense got torched by Aaron Rodgers last week. Indy’s Philip Rivers will not do the same… MINNESOTA 23, INDIANAPOLIS 20


Buffalo Bills @ Miami Dolphins
The Bills will be a force to be reckoned with in 2020. The defense is awesome. QB Josh Allen is a rising star and the running game is one of the NFL’s best. Miami may surprise some teams along the way in 2020, but Buffalo in Week 2 won’t be one of them… BUFFALO 24, MIAMI 13


San Francisco 49ers @ NY Jets
The 49ers were surprised by the Cardinals in Week 1. The Jets…well…they’ve got nowhere to go but up. New York won’t have RB Le’Veon Bell and they will face a San Francisco defense that will be looking to improve upon giving up 400-plus total yards last week. It’s tough on west coast teams traveling to the east coast, but the Niners are simply better… SAN FRANCISCO 34, N.Y. JETS 13


LA Rams @ Philadelphia Eagles
The Rams looked good in a win over Dallas last week. Traveling east to Philadelphia is difficult though. The Eagles gave up eight sacks in a loss to Washington. The Rams pass rush is better. The Eagles have won all six games with the Rams dating back to 2005. That includes back-to-back wins in 2017 and 2018 in L.A. The Rams return the favor in 2020… L.A. RAMS 34, PHILADELPHIA 30


Kansas City Chiefs @ LA Chargers
Chiefs head coach Andy Reid does very well against the other teams in the AFC West. The Chargers have a washed up quarterback and barely beat the Bengals, a team that went 2-14 last year, in Week 1. Kansas City put up 34 points against Houston last week and didn’t play all that well… KANSAS CITY 33, L.A. CHARGERS 17


Baltimore Ravens @ Houston Texans
The Ravens and Texans played last year in a highly anticipated matchup. Baltimore won 41-7. This time the game is in Houston. That won’t make too much of a difference. Lamar Jackson can win anywhere. The Texans beat the Ravens the last two times they have played them at home. Houston will want to make up for last week’s drubbing on national television. Call it an upset… HOUSTON 34, BALTIMORE 33


New England Patriots @ Seattle Seahawks
It’s not often that the Seahawks and Patriots meet. They have only played five times since 2004 and one of those was in a Super Bowl. New England’s offense looks good with Cam Newton at quarterback. Playing at Seattle will not be as big of a challenge without the 12th man – the crowd. Still, the Seahawks have MVP candidate Russell Wilson at quarterback and a defense that can stop the run… SEATTLE 25, NEW ENGLAND 20


New Orleans Saints @ Las Vegas Raiders
It’s the first-ever home game in Las Vegas albeit without fans. The Raiders are still trying to find their way under head coach Jon Gruden. They’ve got an outstanding running back in Josh Jacobs who scored three touchdowns last week. The Saints will play without WR Michael Thomas. That may allow the Raiders to keep it close, but the better team wins in the end… NEW ORLEANS 27, LAS VEGAS 24

2019 GAME Predictions


Tampa Bay bucs - Carolina Panthers
Sunday, September 12th, 2019
Betting Line: Panthers -6.5, O/U 50.5

Neither of these teams wants to be 0-2 after two weeks. Carolina has owned the series lately winning nine of the last 12 games. The Bucs offense was awful last week, particularly QB Jameis Winston who threw three interceptions. Two of those picks were returned for touchdowns. Christian McCaffrey totaled over 200 yards of offense last week and will be too much for the Bucs to handle… Carolina 38, Tampa Bay 17.

San Francisco 49ers - Cincinnati Bengals
Sunday, September 15th, 2019
Betting Line: Bangels -1, O/U 45

The 49ers defense helped San Francisco notch its first win of the season last week. The Niners returned two picks for scores. The offense needs to step it up against a Bengals team that played Seattle very close last week. The Bengals led heading into the fourth quarter. Cincinnati has won two of the last three against San Francisco when playing the Niners at home…Cincinnati 23, San Francisco 20

Los Angeles Chargers - Detroit Lions
Sunday, September 15th, 2019
Betting Line: Chargers -2.5, O/U 47

The Lions started the 2019 season by kissing their sister. Well, not exactly, but they may as well have when they squandered a lead and ended up tying Arizona 27-all. The Chargers comes to town as the favorite on the heels of an impressive 30-24 win over Indianapolis. This doesn’t make sense, but neither do the Lions. Remember last year when they beat New England on Monday night? Detroit 33, LA Chargers 30

Minnesota Vikings - Green Bay Packers
Sunday, September 15th, 2019
Betting Line: Packers -2.5, O/U 45.5

A good old-fashioned NFC North showdown. The Packers beat the Bears in the NFL kickoff game and the Vikings pounded the ball – running 38 times for 172 yards – in a 28-12 win over Atlanta. The Packers managed only 10 points against the Bears but held Chicago to just three. Green Bay hasn’t beaten Minnesota since 2016 and hasn’t won in Minnesota since 2015… Minnesota 21, Green Bay 17

Indianapolis Colts - Tennessee Titans
Sunday, September 15th, 2019
Betting Line: Bangels -3, O/U 44.5

It’s just Week 2, but this game has huge ramifications for the AFC South. The Colts dropped a close one to the Chargers last week while the Titans are 1-0 after destroying Cleveland. Titans RB Derrick Henry was outstanding with 84 yards rushing and a 75-yard TD reception last week. Both teams will look to run the football. Indy won both games last season. Tennessee wins this one at home… Tennessee 23, Indianapolis 20

New England Patriots - Miami Dolphins
Sunday, September 15th, 2019
Betting Line: Patriots -19, O/U 47.5

The defending Super Bowl champion Patriots were masterful in a 30-3 dismantling of the Pittsburgh Steelers in Week 1. Miami showed it might have the worst defense in the NFL after the Dolphins gave up 643 yards and 59 points to Baltimore. Dating back to 2010, Miami has just five wins over the Patriots and a handful came at the end of a season when New England was resting starters for the playoffs… New England 35, Miami 17

Kansas City Chiefs - Oakland Raiders
Sunday, September 15th, 2019
Betting Line: Chiefs -8.5, O/U 52

An early season Raiders-Chiefs matchup got a lot more interesting when Oakland got the best of Denver last Monday night. The whole Antonio Brown saga is over and head coach Jon Gruden appears to be getting the best out of QB Derek Carr and rookie RB Josh Jacobs. The Chiefs lost WR Tyreek Hill for at least a few weeks with a shoulder injury. Sammy Watkins stepped in at caught three Patrick Mahomes TD passes. Mahomes does have a sprained ankle. It might be upset time… Oakland 34, Kansas City 33.

Chicago Bears - Denver Broncos
Sunday, September 15th, 2019
Betting Line: Bears -2.5, O/U 40.5

Both Chicago and Denver experienced some problems in offense in their season openers. The Bears managed a single field goal in a loss to Green Bay. The Denver defense allowed Oakland 10-of-14 third down conversions in their Monday night loss. The Broncos didn’t score until well into the third quarter and then it was just a pair of field goals. We’ll go with the better defense in this one… Chicago 17, Denver 13.

New Orleans Saings - Los Angeles Rams
Sunday, September 15th, 2019
Betting Line: Rams -3, O/U 54

This could be a preview of another NFC championship game. The two teams battled in last year’s conference title game, a 26-23 Rams win over the Saints. In the regular season last year, the Saints outlasted the Rams 45-35. There will surely be some points scored in this one. Saints QB Drew Brees threw for 370 yards in the team’s opener and the Rams scored 30 points in their season-opening win. The home team gets the advantage… LA Rams 44, New Orleans 42.

Philadelphia Eagles - Atlanta Falcons
Sunday, September 15th, 2019
Betting Line: Eagles -1.5, O/U 51

The Atlanta Falcons are in trouble after losing first-round draft pick Chris Lindstrom. The Falcons offensive line is now in disarray, which creates a problem heading into Sunday night’s game with Philadelphia. The Eagles offense is in midseason form after posting 436 yards and 32 points in a win over Washington last week. Atlanta just has too many issues… Philadelphia 29, Atlanta 20.

Cleveland Browns - New York Jets
Monday, September 16th, 2019
Betting Line: Browns -2.5, O/U 45.5

For all the hype that encompassed the Browns in the offseason, they laid an egg in Week 1 losing to Tennessee badly. The Jets received similar hype. Le’Veon Bell in a Jets uniform, an improved defense, etc. Then, New York figured out a way to blow a 16-point lead in their opener and lose to Buffalo. This could be the least-watched Monday night game in history… Cleveland 27, NY Jets 23.

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